A Theoretical Analysis of Endocochlear Potential (EP)
نویسندگان
چکیده
منابع مشابه
Stria vascularis as source of endocochlear potential.
IT IS WELL KNOWN (1, 2, 12, 6) that, when a recording microelectrode is pushed into the endolympatic space of the cochlea of a guinea pig or a cat, the potential at the tip of the electrode rises 70-90 mV. above the potential level in the perilymphatic space. Although the ionic composition of the endolymph is unique among various body fluids because of its high potassium content (lo), the DC po...
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Acoustic stimulation gates mechanically sensitive ion channels in cochlear sensory hair cells. Even in the absence of sound, a fraction of these channels remains open, forming a conductance between hair cells and the adjacent fluid space, scala media. Restoring the lost endogenous polarization of scala media in an in vitro preparation of the whole cochlea depolarizes the hair cell soma. Using b...
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Sensory transduction in the cochlea and the vestibular labyrinth depends on the cycling of K+. In the cochlea, endolymphatic K+ flows into the sensory hair cells via the apical transduction channel and is released from the hair cells into perilymph via basolateral K+ channels including KCNQ4. K+ may be taken up by fibrocytes in the spiral ligament and transported from cell to cell via gap junct...
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ژورنال
عنوان ژورنال: Practica Oto-Rhino-Laryngologica
سال: 1983
ISSN: 1884-4545,0032-6313
DOI: 10.5631/jibirin.76.2special_407